On Novel Features of the Proton Leak and Possibility of Uncoupling Population of Mitochondria in Brown Adipose Tissue.

On Novel Features of the Proton Leak and Possibility of Uncoupling Population of Mitochondria in Brown Adipose Tissue.
Daraja:
Oliy ta`lim
Turi:
Maqola
Til:
Ingliz tilida
Yaratilgan vaqti:
2021-04-20 04:43:52
In many studies on succinate as a substrate, the respiration of brown adipose tissue mitochondria is partially uncoupled that is associated with proton leak. NAD-dependent substrates (pyruvate + malate) were also used in a number of works. Oxidation of NAD-dependent substrates occurs with greater coupling where the respiration rate is higher and state 4 (resting state of mitochondrial respiration) lower than that with succinate. It is suggested that the oxidation of these substrates occurs in different ways.

Дабавлено : 2021-04-20 04:43:52

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