Nowadays. ideniitlcaiion orsnihciie cannabinoids in the "spices" which are a pan of arious objects ofillicil movement through a customs border of the Republic of Uzbekistan is a complex challenge and requires use of modern high-informative methods of research. There are approaches directed on detection and determination of sev eral chosen target analytes, and also more difUcult methods of detection of groups of the unknown substances close on chemical structure. A group of anaivtical methods, especially for idcniillcation of substances, prov ide use of instrument prov iding and require longer time.