Headache is as old as the world , it at least once in a lifetime experiences every inhabitant of the planet . In the general population , there is a high incidence of primary headaches (PHB ) . Leading place takes migraine prevalence is highest in the most working age ( Tabeeva GR, 2013 , LiptonRB., StewartWS., DiamondS., Etal., 2001). Migraine is an episodic form of primary headache , which is manifested by intense , often unilateral paroxysmal headaches , as well as neurological, gastrointestinal , autonomic disturbances.